From Semirational to Rational Design: Developing a Substrate-Coupled System of Glucose Dehydrogenase for Asymmetric Synthesis

Glucose dehydrogenase (GDH) generally functions as an expensive cofactor NAD­(P)H regenerator in an enzyme-coupled cofactor regeneration system, as in the production of fine chemicals. However, whether GDH can accept substrates other than glucose remains to be explored. Based on a known mutant of GD...

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Veröffentlicht in:	ACS catalysis 2022-06, Vol.12 (11), p.6746-6755
Hauptverfasser:	Yan, Qipeng, Zhang, Xinhua, Chen, Yingzhuang, Guo, Bin, Zhou, Pei, Chen, Bo, Huang, Qun, Wang, Jian-bo
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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