Cothreading of Unmodified and Monoazidated β‑Cyclodextrins in Polyrotaxanes for Orthogonal Modification of Cell-Penetrating Peptides via Click Chemistry

To establish a method for the orthogonal chemical functionalization of β-cyclodextrin (β-CD)-based polyrotaxane (PRX), unmodified and monoazidated β-CDs (N3-β-CDs) were utilized as cyclic host molecules for synthesizing PRXs. PRXs were successfully synthesized by using N3-β-CD, and the molar ratio o...

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Veröffentlicht in:ACS applied polymer materials 2022-05, Vol.4 (5), p.3866-3876
Hauptverfasser: Zhang, Shunyao, Tamura, Atsushi, Yui, Nobuhiko
Format: Artikel
Sprache:eng
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