p65 siRNA-Loaded Buformin/DNA Nanoprisms Alleviate Acute Lung Injury through Inhibiting NLRP3-Mediated Pyroptosis

Acute lung injury (ALI) and acute respiratory distress syndrome are triggered by complicated molecular mechanisms, which are the prime causes of high mortality in critical patients. Recent research suggests that the release of high levels of IL-1β and IL-18, resulting from pyroptosis, plays a pivota...

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Veröffentlicht in:ACS applied nano materials 2023-11, Vol.6 (21), p.20099-20110
Hauptverfasser: You, Qianyi, Hu, Qiao, Huang, Chaowang, Xu, Jing, Guo, Yawen, Wang, Dan, Chen, Xiaolong, Qian, Hang, Hu, Mingdong
Format: Artikel
Sprache:eng
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