Amphiphilic Polymeric Nanoparticles Modified with a Protease-Resistant Peptide Shuttle for the Delivery of SN-38 in Diffuse Intrinsic Pontine Glioma

Diffuse intrinsic pontine glioma (DIPG) is a chemo-resistant, incurable pediatric tumor of the central nervous system (CNS). The blood–brain barrier (BBB) remains intact in the course of the disease, preventing drugs from entering the brain and resulting in therapeutic failure. The topoisomerase I i...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	ACS applied nano materials 2021-02, Vol.4 (2), p.1314-1329
Hauptverfasser:	Bukchin, Alexandra, Sanchez-Navarro, Macarena, Carrera, Adam, Resa-Pares, Claudia, Castillo-Ecija, Helena, Balaguer-Lluna, Leire, Teixidó, Meritxell, Olaciregui, Nagore G, Giralt, Ernest, Carcaboso, Angel M, Sosnik, Alejandro
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!