Troubleshooting When Using γ‑Valerolactone (GVL) in Green Solid-Phase Peptide Synthesis

The synthesis of peptides for both research and API production is conveniently carried out using the solid-phase strategy. However, the main drawback of this approach is the large amounts of hazardous solvents required. In this regard, several pharmaceutical industries participating in the ACS Green...

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Veröffentlicht in:Organic process research & development 2019-05, Vol.23 (5), p.1096-1100
Hauptverfasser: Kumar, Ashish, Thompson-Adewumi, Adeniyi, Nandhini, K. P, Collins, Jonathan M, Albericio, Fernando, de la Torre, Beatriz G
Format: Artikel
Sprache:eng
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