Review of Synthetic Routes and Final Forms of Integrase Inhibitors Dolutegravir, Cabotegravir, and Bictegravir

Bictegravir and dolutegravir are two recently approved integrase inhibitors for the treatment of HIV. A third inhibitor, cabotegravir, is in Phase 3 development. As a continuation of a series of articles on synthetic routes to newly approved drugs, the current article reviews the patent and journal...

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Veröffentlicht in:Organic process research & development 2019-05, Vol.23 (5), p.716-729
1. Verfasser: Hughes, David L
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
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