Optimization of Manganese Coupling Reaction for Kilogram-Scale Preparation of Two Aryl-1,3-dione Building Blocks

Aryl-1,3-diones represent a promising new class of herbicidal acetyl-CoA carboxylase (ACCase) inhibitors. The original synthesis of this structural motif employed in the research phase involved a selenium oxide mediated oxidation, the use of diazoacetate and aryl lead reagents, and a low temperature...

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Veröffentlicht in:Organic process research & development 2017-10, Vol.21 (10), p.1625-1632
Hauptverfasser: Smejkal, Tomas, Gopalsamuthiram, Vijayagopal, Ghorai, Sujit K, Jawalekar, Anup M, Pagar, Dinesh, Sawant, Krishna, Subramanian, Srinivas, Dallimore, Jonathan, Willetts, Nigel, Scutt, James N, Whalley, Louisa, Hotson, Matthew, Hogan, Anne-Marie, Hodges, George
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Sprache:eng
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