Monitoring Continuous Crystallization of Paracetamol in the Presence of an Additive Using an Integrated PAT Array and Multivariate Methods

In this study, an automated intelligent decision support (IDS) framework was applied to monitor the continuous crystallization of form I paracetamol (PCM) and determine steady-state operation. A modified single-stage mixed suspension mixed product removal (MSMPR) crystallizer was used to investigate...

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Veröffentlicht in:	Organic process research & development 2016-03, Vol.20 (3), p.626-636
Hauptverfasser:	Powell, Keddon A, Saleemi, Ali N, Rielly, Chris D, Nagy, Zoltan K
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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