Precise Control of the Oxidation Reaction in a High-Purity Dexlansoprazole Synthesis Process Using In Situ Infrared

Dexlansoprazole is a second-generation proton pump inhibitor, which is used to treat gastroesophageal reflux disease and erosive esophagitis. It is usually synthesized by asymmetric sulfur oxidation through the Kagan reaction. However, due to the difficulty in controlling the degree of sulfur oxidat...

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Veröffentlicht in:	Organic process research & development 2023-06, Vol.27 (6), p.1122-1128
Hauptverfasser:	Wang, Chunchao, Wang, Haoyu, Huang, Cheng, Wu, Chengjun, Sun, Tiemin
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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