A Safer Synthesis of the Explosive Precursors 4‑Aminofurazan-3-Carboxylic Acid and its Ethyl Ester Derivative

A safe and efficient one-pot synthesis of 4-aminofurazan-3-carboxylic acid and its hydrogen chloride gas-free conversion to the ethyl ester derivative are described. Previous syntheses of these intermediates were plagued with mischaracterization issues, low yields, and/or dangerous exothermic profil...

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Veröffentlicht in:	Organic process research & development 2020-04, Vol.24 (4), p.599-603
Hauptverfasser:	Miller, Christopher W, Johnson, Eric C, Sausa, Rosario C, Orlicki, Joshua A, Sabatini, Jesse J
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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