Preclinical Nanomedicines for Polyglutamine-Based Neurodegenerative Diseases

Polyglutamine (polyQ) diseases, such as Huntington’s disease and several types of spinocerebellar ataxias, are dominantly inherited progressive neurodegenerative disorders and characterized by the presence of expanded CAG trinucleotide repeats in the respective disease locus of the patient genomes....

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Veröffentlicht in:	Molecular pharmaceutics 2021-02, Vol.18 (2), p.610-626
Hauptverfasser:	Lee, Leo Kit Cheung, Leong, Lok I, Liu, Yao, Luo, Meihua, Chan, Ho Yin Edwin, Choi, Chung Hang Jonathan
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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