Incorporation of D 2 O-Induced Fluorine Chemical Shift Perturbations into Ensemble-Structure Characterization of the ERalpha Disordered Region

Structural characterization of intrinsically disordered proteins (IDPs) requires a concerted effort between experiments and computations by accounting for their conformational heterogeneity. Given the diversity of experimental tools providing local and global structural information, constructing an...

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Veröffentlicht in:	The journal of physical chemistry. B 2022-11, Vol.126 (45), p.9176-9186
Hauptverfasser:	Zheng, Wenwei, Du, Zhanwen, Ko, Soo Bin, Wickramasinghe, Nalinda P, Yang, Sichun
Format:	Artikel
Sprache:	eng
Schlagworte:	Estrogen Receptor alpha Fluorine Intrinsically Disordered Proteins - chemistry Protein Conformation Scattering, Small Angle Solvents X-Ray Diffraction
Online-Zugang:	Volltext
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