Enzyme-Catalyzed Asymmetric Domino Thia-Michael/Aldol Condensation Using Pepsin

The novel catalytic promiscuity of pepsin from porcine gastric mucosa for the asymmetric catalysis of the domino thia-Michael/aldol condensation reaction in MeCN and buffer was discovered for the first time. Broad substrate specificity was tested, and a series of corresponding products were obtained...

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Veröffentlicht in:	Journal of organic chemistry 2016-07, Vol.81 (14), p.6042-6048
Hauptverfasser:	Xiang, Yang, Song, Jian, Zhang, Yong, Yang, Da-Cheng, Guan, Zhi, He, Yan-Hong
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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