68 Ga-Labeled TRAP-Based Glycoside Trimers for Imaging of the Functional Liver Reserve

The exclusive asialoglycoprotein receptor (ASGR) expression on hepatocytes makes it an attractive target for imaging of the functional liver reserve. Here, we present a set of TRAP-based glycoside trimers and evaluate their imaging properties compared to the gold standard [ Tc]Tc-GSA. The click-chem...

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Veröffentlicht in:Journal of medicinal chemistry 2024-11, Vol.67 (21), p.19668-19677
Hauptverfasser: Zierke, Maximilian A, Rangger, Christine, Samadikhah, Kimia, Kreutz, Christoph, Schmid, Andreas M, Haubner, Roland
Format: Artikel
Sprache:eng
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