New Potent RIPK2 Inhibitors as a Promising Therapeutic Avenue for Colitis Through the Blockade of NOD Inflammatory Pathways

Inflammatory bowel diseases (IBDs) are conditions characterized by chronic inflammation of the bowel. Receptor-interacting Ser/Thr protein kinase 2, a key mediator in nucleotide oligomerization domain (NOD)-like receptor (NLRs) 1 (NOD1) and NOD2 inflammatory pathways, has been shown to be involved i...

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Veröffentlicht in:	Journal of medicinal chemistry 2024-10, Vol.67 (19), p.17407-17428
Hauptverfasser:	Rivoal, Morgane, Barzyck, Amélie, Six, Perrine, Dezitter, Xavier, Cornu-Choi, Min-Jeong, Body-Malapel, Mathilde, Djouina, Madjid, Waxin, Christophe, Dubuquoy, Laurent, Millet, Régis, Leleu-Chavain, Natascha
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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