Hepatotoxicity in Cattle Associated with Salvia reflexa Diterpenes, including 7‑Hydroxyrhyacophiline, a New Seco-Clerodane Diterpene

A case of baled alfalfa hay contaminated with multiple weeds induced hepatotoxicity and death in cattle. The hepatotoxic compounds were isolated by bioassay-guided fractionation using a mouse model and identified as salviarin, salvianduline D, rhyacophiline, and 7-hydroxyrhyacophiline. The structure...

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Veröffentlicht in:Journal of agricultural and food chemistry 2021-02, Vol.69 (4), p.1251-1258
Hauptverfasser: Gardner, Dale R, Panter, Kip E, Stegelmeier, Bryan L, Stonecipher, Clinton A
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Sprache:eng
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