Pharmacokinetic Interactions of a Hop Dietary Supplement with Drug Metabolism in Perimenopausal and Postmenopausal Women

Botanical dietary supplements produced from hops (Humulus lupulus) containing the chemopreventive compound xanthohumol and phytoestrogen 8-prenylnaringenin are used by women to manage menopausal symptoms. Because of the long half-lives of prenylated hop phenols and reports that they inhibit certain...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2020-05, Vol.68 (18), p.5212-5220
Hauptverfasser:	van Breemen, Richard B, Chen, Luying, Tonsing-Carter, Alyssa, Banuvar, Suzanne, Barengolts, Elena, Viana, Marlos, Chen, Shao-Nong, Pauli, Guido F, Bolton, Judy L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Caffeine - pharmacokinetics Cytochrome P-450 Enzyme System - genetics Cytochrome P-450 Enzyme System - metabolism Dextromethorphan - pharmacokinetics Dietary Supplements - analysis Female Herb-Drug Interactions Humans Humulus - chemistry Middle Aged Perimenopause - drug effects Perimenopause - genetics Perimenopause - metabolism Plant Extracts - administration & dosage Plant Extracts - pharmacokinetics Postmenopause - drug effects Postmenopause - genetics Postmenopause - metabolism Tolbutamide - pharmacokinetics
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