Up-Regulation of T‑Cell Activation MicroRNAs in Drug-Specific CD4+ T‑Cells from Hypersensitive Patients

Dysregulation in the expression of microRNAs (miRNAs), single-stranded RNAs which regulate gene expression, has been associated with diseases such as Stevens–Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN), although their cellular origin has not been explored. Thus, the focus of this work wa...

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Veröffentlicht in:Chemical research in toxicology 2018-06, Vol.31 (6), p.454-461
Hauptverfasser: Monroy-Arreola, Alejandra, Durán-Figueroa, Noé V, Méndez-Flores, Silvia, Domínguez-Cherit, Judith, Watkinson, Joel, Badillo-Corona, Jesús A, Whitaker, Paul, Naisbitt, Dean J, Castrejón-Flores, José L
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Sprache:eng
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