Inhibition of Hepatobiliary Transport Activity by the Antibacterial Agent Fusidic Acid: Insights into Factors Contributing to Conjugated Hyperbilirubinemia/Cholestasis

Conjugated hyperbilirubinemia accompanied by cholestasis is a frequent side effect during chronic treatment with the antimicrobial agent fusidic acid. Previous studies from our laboratory, addressing mechanisms of musculoskeletal toxicity arising from coadministration of fusidic acid with statins, d...

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Veröffentlicht in:	Chemical research in toxicology 2016-10, Vol.29 (10), p.1778-1788
Hauptverfasser:	Lapham, Kimberly, Novak, Jonathan, Marroquin, Lisa D, Swiss, Rachel, Qin, Shuzhen, Strock, Christopher J, Scialis, Renato, Aleo, Michael D, Schroeter, Thomas, Eng, Heather, Rodrigues, A. David, Kalgutkar, Amit S
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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