Understanding Polymorphic Control of Pharmaceuticals Using Imidazolium-Based Ionic Liquid Mixtures as Crystallization Directing Agents

Imidazolium-based room temperature ionic liquids (RTILs) were tested to assess their ability to control molecular polymorphic behavior. Mixtures of RTILs with distinct cation/anion combinations revealed promising capabilities in directing the crystallization process toward less stable polymorphs. In...

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Veröffentlicht in:Crystal growth & design 2017-02, Vol.17 (2), p.428-432
Hauptverfasser: Martins, Inês C. B, Gomes, José R. B, Duarte, M. Teresa, Mafra, Luís
Format: Artikel
Sprache:eng
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