Chiral Resolution of RS-Praziquantel via Diastereomeric Co-Crystal Pair Formation with l‑Malic Acid

Praziquantel (PZQ) is an important chiral active pharmaceutical ingredient for the treatment of gastrointestinal parasites, which is commercially available only in the form of its racemate. In this article, on the basis of co-crystallization experiments a convenient two-step protocol for the chiral...

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Veröffentlicht in:	Crystal growth & design 2016-01, Vol.16 (1), p.307-314
Hauptverfasser:	Sánchez-Guadarrama, Obdulia, Mendoza-Navarro, Fabiola, Cedillo-Cruz, Alberto, Jung-Cook, Helgi, Arenas-García, Jenniffer I, Delgado-Díaz, Alejandra, Herrera-Ruiz, Dea, Morales-Rojas, Hugo, Höpfl, Herbert
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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