Polymorphic Phase Transformations in Crystalline Solid Dispersions: The Combined Effect of Pressure and Temperature

Potential polymorphic phase transformations (PPTs) during the processing of active pharmaceutical ingredients (APIs) have limited the application of hot-melt extrusion (HME) and three-dimensional printing (3DP) as alternative technologies to enable polymer-based formulations such as crystalline soli...

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Veröffentlicht in:Crystal growth & design 2022-05, Vol.22 (5), p.2903-2909
Hauptverfasser: Reyes Figueroa, Francheska, Hernández Espinell, José R, Hernández, Marileyda Hernández, López-Mejías, Vilmalí, Stelzer, Torsten
Format: Artikel
Sprache:eng
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