Amino–Imino Tautomerism in the Salt Formation of Albendazole: Hydrobromide and Nitrate Salts

Albendazole (ABZ) is a poorly soluble anthelmintic drug that can exist in amine and imine desmotropic forms. These facts can affect the solubility and bioavailability of the drug product. Here, we investigate the salt formation of ABZ with the acids HCl, HBr, and HNO3 associated with the tautomerism...

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Veröffentlicht in:	Crystal growth & design 2021-02, Vol.21 (2), p.1122-1135
Hauptverfasser:	Carvalho, Paulo de S, Diniz, Luan F, da Silva, Gelson T. S. T, Coutinho, Nayara Dantas, dos Santos, Priscila Gomes, Carvalho-Silva, Valter Henrique, Ribeiro, Caue, Ellena, Javier
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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