Polymorphic Control and Scale-Up Strategy for Antisolvent Crystallization Using Direct Nucleation Control

In this work, a scale-up strategy based on the principles of direct design and quality-by-control (QbC) was applied and investigated using direct nucleation control (DNC). Process analytical technologies (PATs) were implemented for process monitoring and control. Antisolvent crystallization of indom...

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Veröffentlicht in:	Crystal growth & design 2020-04, Vol.20 (4), p.2683-2697
Hauptverfasser:	Ostergaard, Iben, Szilagyi, Botond, de Diego, Heidi Lopez, Qu, Haiyan, Nagy, Zoltan K
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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