Trojan Horse for Light-Triggered Bifurcated Production of Singlet Oxygen and Fenton-Reactive Iron within Cancer Cells

Traditional photodynamic therapy for cancer relies on dye-photosensitized generation of singlet oxygen. However, therapeutically effective singlet oxygen generation requires well-oxygenated tissues, whereas many tumor environments tend to be hypoxic. We describe a platform for targeted enhancement o...

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Veröffentlicht in:	Biomacromolecules 2018-01, Vol.19 (1), p.178-187
Hauptverfasser:	Cioloboc, Daniela, Kennedy, Christopher, Boice, Emily N, Clark, Emily R, Kurtz, Donald M
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line, Tumor Humans Hydrogen Peroxide - metabolism Iron - metabolism Light Melanoma - metabolism Melanoma - pathology Singlet Oxygen - metabolism Skin Neoplasms - metabolism Skin Neoplasms - pathology Spectrophotometry, Ultraviolet
Online-Zugang:	Volltext
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