Extension of elution range in micellar electrokinetic capillary chromatography
The authors have successfully demonstrated one approach to extend elution range in micellar electrokinetic capillary chromatography (MECC). By silanating the surfaces of fused-silica capillaries with trimethylchlorosilane (TMCS) the authors lowered electroosmotic flow velocity and, more importantly,...
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| Veröffentlicht in: | Anal. Chem.; (United States) 1987-05, Vol.59 (10), p.1466-1470 |
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| container_end_page | 1470 |
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| container_issue | 10 |
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| container_title | Anal. Chem.; (United States) |
| container_volume | 59 |
| creator | Balchunas, A. T Sepaniak, M. J |
| description | The authors have successfully demonstrated one approach to extend elution range in micellar electrokinetic capillary chromatography (MECC). By silanating the surfaces of fused-silica capillaries with trimethylchlorosilane (TMCS) the authors lowered electroosmotic flow velocity and, more importantly, the net flow velocity of the micelle phase, thereby increasing elution range. This is accomplished at the expense of a loss in column efficiency which primarily results from solute-wall interactions. Addition of 2-propanol to the mobile phase serves to minimize this effect, thereby restoring much of the efficiency lost in the process. |
| doi_str_mv | 10.1021/ac00137a020 |
| format | Article |
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T ; Sepaniak, M. J</creator><creatorcontrib>Balchunas, A. T ; Sepaniak, M. J ; Univ. of Tennessee, Knoxville</creatorcontrib><description>The authors have successfully demonstrated one approach to extend elution range in micellar electrokinetic capillary chromatography (MECC). By silanating the surfaces of fused-silica capillaries with trimethylchlorosilane (TMCS) the authors lowered electroosmotic flow velocity and, more importantly, the net flow velocity of the micelle phase, thereby increasing elution range. This is accomplished at the expense of a loss in column efficiency which primarily results from solute-wall interactions. Addition of 2-propanol to the mobile phase serves to minimize this effect, thereby restoring much of the efficiency lost in the process.</description><identifier>ISSN: 0003-2700</identifier><identifier>EISSN: 1520-6882</identifier><identifier>DOI: 10.1021/ac00137a020</identifier><identifier>CODEN: ANCHAM</identifier><language>eng</language><publisher>Washington, DC: American Chemical Society</publisher><subject>400105 - Separation Procedures ; AMINES ; Analytical chemistry ; BLOOD VESSELS ; BODY ; CAPILLARIES ; CARDIOVASCULAR SYSTEM ; Chemistry ; Chromatographic methods and physical methods associated with chromatography ; CHROMATOGRAPHY ; DATA ; EFFICIENCY ; ELECTROPHORESIS ; ELUTRIATION ; Exact sciences and technology ; EXPERIMENTAL DATA ; FLOW RATE ; INFORMATION ; INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY ; LIQUID COLUMN CHROMATOGRAPHY ; MICELLAR SYSTEMS ; NUMERICAL DATA ; ORGANIC COMPOUNDS ; ORGANS ; Other chromatographic methods ; SEPARATION PROCESSES ; SOLUTES ; SURFACTANTS ; VELOCITY</subject><ispartof>Anal. 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T</creatorcontrib><creatorcontrib>Sepaniak, M. J</creatorcontrib><creatorcontrib>Univ. of Tennessee, Knoxville</creatorcontrib><title>Extension of elution range in micellar electrokinetic capillary chromatography</title><title>Anal. Chem.; (United States)</title><addtitle>Anal. Chem</addtitle><description>The authors have successfully demonstrated one approach to extend elution range in micellar electrokinetic capillary chromatography (MECC). By silanating the surfaces of fused-silica capillaries with trimethylchlorosilane (TMCS) the authors lowered electroosmotic flow velocity and, more importantly, the net flow velocity of the micelle phase, thereby increasing elution range. This is accomplished at the expense of a loss in column efficiency which primarily results from solute-wall interactions. Addition of 2-propanol to the mobile phase serves to minimize this effect, thereby restoring much of the efficiency lost in the process.</description><subject>400105 - Separation Procedures</subject><subject>AMINES</subject><subject>Analytical chemistry</subject><subject>BLOOD VESSELS</subject><subject>BODY</subject><subject>CAPILLARIES</subject><subject>CARDIOVASCULAR SYSTEM</subject><subject>Chemistry</subject><subject>Chromatographic methods and physical methods associated with chromatography</subject><subject>CHROMATOGRAPHY</subject><subject>DATA</subject><subject>EFFICIENCY</subject><subject>ELECTROPHORESIS</subject><subject>ELUTRIATION</subject><subject>Exact sciences and technology</subject><subject>EXPERIMENTAL DATA</subject><subject>FLOW RATE</subject><subject>INFORMATION</subject><subject>INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY</subject><subject>LIQUID COLUMN CHROMATOGRAPHY</subject><subject>MICELLAR SYSTEMS</subject><subject>NUMERICAL DATA</subject><subject>ORGANIC COMPOUNDS</subject><subject>ORGANS</subject><subject>Other chromatographic methods</subject><subject>SEPARATION PROCESSES</subject><subject>SOLUTES</subject><subject>SURFACTANTS</subject><subject>VELOCITY</subject><issn>0003-2700</issn><issn>1520-6882</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><recordid>eNptkF9LwzAUxYMoOKdPfoEigg9SvWnaNH2UsTlhqODEx5Ddplu2rhlJBP32ZlSGDz7dP-d3L4dDyCWFOwoZvVcIQFmpIIMjMqBFBikXIjsmAwBgaVYCnJIz79cRo0D5gDyPv4LuvLFdYptEt59h3zrVLXViumRrULetclHRGJzdmE4HgwmqndnvvxNcObtVwS6d2q2-z8lJo1qvL37rkLxPxvPRNJ29PD6NHmapyjMWUqqrBS4WdYMl1AK5oHUUFg0HJShlXEBe50LlrAaWVw3uR15nrGA141pxNiRX_V_rg5EeTdC4Qtt10aXkRU5FCRG67SF01nunG7lzZhtNSwpyn5f8k1ekr3t6pzyqtokZoPGHE8F4VfEiYmmPGR_010FWbiN5ycpCzl_fZPYxyUfiGeQ08jc9r9DLtf10XczlXwM_Mo-F5g</recordid><startdate>19870515</startdate><enddate>19870515</enddate><creator>Balchunas, A. T</creator><creator>Sepaniak, M. J</creator><general>American Chemical Society</general><scope>BSCLL</scope><scope>IQODW</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>OTOTI</scope></search><sort><creationdate>19870515</creationdate><title>Extension of elution range in micellar electrokinetic capillary chromatography</title><author>Balchunas, A. T ; Sepaniak, M. J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a423t-1e9bcbbdfc70d8c681da42bf60a81136804d48a43d0349fc04d46d2353d36ea63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>400105 - Separation Procedures</topic><topic>AMINES</topic><topic>Analytical chemistry</topic><topic>BLOOD VESSELS</topic><topic>BODY</topic><topic>CAPILLARIES</topic><topic>CARDIOVASCULAR SYSTEM</topic><topic>Chemistry</topic><topic>Chromatographic methods and physical methods associated with chromatography</topic><topic>CHROMATOGRAPHY</topic><topic>DATA</topic><topic>EFFICIENCY</topic><topic>ELECTROPHORESIS</topic><topic>ELUTRIATION</topic><topic>Exact sciences and technology</topic><topic>EXPERIMENTAL DATA</topic><topic>FLOW RATE</topic><topic>INFORMATION</topic><topic>INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY</topic><topic>LIQUID COLUMN CHROMATOGRAPHY</topic><topic>MICELLAR SYSTEMS</topic><topic>NUMERICAL DATA</topic><topic>ORGANIC COMPOUNDS</topic><topic>ORGANS</topic><topic>Other chromatographic methods</topic><topic>SEPARATION PROCESSES</topic><topic>SOLUTES</topic><topic>SURFACTANTS</topic><topic>VELOCITY</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Balchunas, A. T</creatorcontrib><creatorcontrib>Sepaniak, M. J</creatorcontrib><creatorcontrib>Univ. of Tennessee, Knoxville</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>CrossRef</collection><collection>OSTI.GOV</collection><jtitle>Anal. Chem.; (United States)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Balchunas, A. T</au><au>Sepaniak, M. J</au><aucorp>Univ. of Tennessee, Knoxville</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Extension of elution range in micellar electrokinetic capillary chromatography</atitle><jtitle>Anal. Chem.; (United States)</jtitle><addtitle>Anal. Chem</addtitle><date>1987-05-15</date><risdate>1987</risdate><volume>59</volume><issue>10</issue><spage>1466</spage><epage>1470</epage><pages>1466-1470</pages><issn>0003-2700</issn><eissn>1520-6882</eissn><coden>ANCHAM</coden><abstract>The authors have successfully demonstrated one approach to extend elution range in micellar electrokinetic capillary chromatography (MECC). By silanating the surfaces of fused-silica capillaries with trimethylchlorosilane (TMCS) the authors lowered electroosmotic flow velocity and, more importantly, the net flow velocity of the micelle phase, thereby increasing elution range. This is accomplished at the expense of a loss in column efficiency which primarily results from solute-wall interactions. Addition of 2-propanol to the mobile phase serves to minimize this effect, thereby restoring much of the efficiency lost in the process.</abstract><cop>Washington, DC</cop><pub>American Chemical Society</pub><doi>10.1021/ac00137a020</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0003-2700 |
| ispartof | Anal. Chem.; (United States), 1987-05, Vol.59 (10), p.1466-1470 |
| issn | 0003-2700 1520-6882 |
| language | eng |
| recordid | cdi_crossref_primary_10_1021_ac00137a020 |
| source | ACS Publications |
| subjects | 400105 - Separation Procedures AMINES Analytical chemistry BLOOD VESSELS BODY CAPILLARIES CARDIOVASCULAR SYSTEM Chemistry Chromatographic methods and physical methods associated with chromatography CHROMATOGRAPHY DATA EFFICIENCY ELECTROPHORESIS ELUTRIATION Exact sciences and technology EXPERIMENTAL DATA FLOW RATE INFORMATION INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY LIQUID COLUMN CHROMATOGRAPHY MICELLAR SYSTEMS NUMERICAL DATA ORGANIC COMPOUNDS ORGANS Other chromatographic methods SEPARATION PROCESSES SOLUTES SURFACTANTS VELOCITY |
| title | Extension of elution range in micellar electrokinetic capillary chromatography |
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