Determination of reactive nitrogen mustard anticancer drugs in plasma by high-performance liquid chromatography using derivatization

A high-performance liquid chromatography (HPLC) method is described for the determination of reactive nitrogen mustard anticancer drugs in plasma after derivatization with diethyl-dithiocarbamic acid (DDTC). Three compounds were studied: two reactive species (mechlorethamine (HN2) and galactose 6-mu...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Analytical chemistry (Washington) 1991-08, Vol.63 (15), p.1514-1519
Hauptverfasser:	Cummings, Jeffrey, MacLellan, Alexander, Smyth, John F, Farmer, Peter B
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Antineoplastic Agents - blood Biological and medical sciences Chromatography, High Pressure Liquid General pharmacology Humans Mechlorethamine - blood Mechlorethamine - chemistry Medical sciences Pharmacology. Drug treatments
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!