Auditory brainstem evoked potentials in asymptomatic lead-exposed subjects

Auditory Brainstem Evoked Potentials (ABEP) were recorded from 29 adults and children, accidentally exposed to lead through food until approximately a year prior to this study. ABEP were recorded in response to 75 dBHL click presented at rates of 10/sec. and 55/sec. Average values were calculated fo...

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Veröffentlicht in:Journal of laryngology and otology 1986-09, Vol.100 (9), p.1031-1036
Hauptverfasser: Holdstein, Y., Pratt, H., Goldsher, M., Rosen, G., Shenhav, R., Linn, S., Mor, A., Barkai, A.
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container_end_page 1036
container_issue 9
container_start_page 1031
container_title Journal of laryngology and otology
container_volume 100
creator Holdstein, Y.
Pratt, H.
Goldsher, M.
Rosen, G.
Shenhav, R.
Linn, S.
Mor, A.
Barkai, A.
description Auditory Brainstem Evoked Potentials (ABEP) were recorded from 29 adults and children, accidentally exposed to lead through food until approximately a year prior to this study. ABEP were recorded in response to 75 dBHL click presented at rates of 10/sec. and 55/sec. Average values were calculated for peak latency and for interpeak latency differences. Average values of the effect of increasing stimulus rate were calculated as well. Similar values were calculated for normative child and adult control groups. IPLD (I-III) showed the most significant and recurring results, with longer intervals in lead-exposed children compared with their control group. Increasing stimulus rate, on the other hand, affected the adult lead-exposed subjects more than the children. These results may imply an impairment of the auditory system with azonal and myelin involvement. ABEP is suggested as a sensitive detector of subclinical lead exposure effects on the nervous system.
doi_str_mv 10.1017/S0022215100100519
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ABEP were recorded in response to 75 dBHL click presented at rates of 10/sec. and 55/sec. Average values were calculated for peak latency and for interpeak latency differences. Average values of the effect of increasing stimulus rate were calculated as well. Similar values were calculated for normative child and adult control groups. IPLD (I-III) showed the most significant and recurring results, with longer intervals in lead-exposed children compared with their control group. Increasing stimulus rate, on the other hand, affected the adult lead-exposed subjects more than the children. These results may imply an impairment of the auditory system with azonal and myelin involvement. 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Laryngol. Otol</addtitle><description>Auditory Brainstem Evoked Potentials (ABEP) were recorded from 29 adults and children, accidentally exposed to lead through food until approximately a year prior to this study. ABEP were recorded in response to 75 dBHL click presented at rates of 10/sec. and 55/sec. Average values were calculated for peak latency and for interpeak latency differences. Average values of the effect of increasing stimulus rate were calculated as well. Similar values were calculated for normative child and adult control groups. IPLD (I-III) showed the most significant and recurring results, with longer intervals in lead-exposed children compared with their control group. Increasing stimulus rate, on the other hand, affected the adult lead-exposed subjects more than the children. These results may imply an impairment of the auditory system with azonal and myelin involvement. 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Toxic occupational diseases</subject><subject>Child</subject><subject>Evoked Potentials, Auditory - drug effects</subject><subject>Female</subject><subject>Humans</subject><subject>Lead Poisoning - diagnosis</subject><subject>Lead Poisoning - physiopathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Metals and various inorganic compounds</subject><subject>Middle Aged</subject><subject>Time Factors</subject><subject>Toxicology</subject><issn>0022-2151</issn><issn>1748-5460</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LAzEURYMotVZ_gAthFm5H8zGZJMtatFUEKypdhiSTkbSdD5IZaf-9KS3dCMKDt7jnPh4HgGsE7xBE7P4DQowxogjCOBSJEzBELOMpzXJ4Coa7ON3l5-AihCWMGIN4AAaE5TDn2RC8jPvCdY3fJtorV4fOVon9aVa2SNqms3Xn1Dokrk5U2FZt11SqcyZZW1WkdtM2IXKh10trunAJzsoI26vDHoGvp8fPySx9fZs-T8avqSEYd6km1hqVaUFzQTgRGeeGFFRgTS1VGUcECmhKSLTmJbes5AXFKGOWKV5SasgIoP1d45sQvC1l612l_FYiKHda5B8tsXOz77S9rmxxbBw8xPz2kKtg1Lr0qjYuHDEmmBA5jVi6x1wUtTnGyq9kzgijMp--y8WM5PhhPpeLyJPDq6rS3hXfVi6b3tdRzz_P_gKes4iJ</recordid><startdate>198609</startdate><enddate>198609</enddate><creator>Holdstein, Y.</creator><creator>Pratt, H.</creator><creator>Goldsher, M.</creator><creator>Rosen, G.</creator><creator>Shenhav, R.</creator><creator>Linn, S.</creator><creator>Mor, A.</creator><creator>Barkai, A.</creator><general>Cambridge University Press</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>198609</creationdate><title>Auditory brainstem evoked potentials in asymptomatic lead-exposed subjects</title><author>Holdstein, Y. ; Pratt, H. ; Goldsher, M. ; Rosen, G. ; Shenhav, R. ; Linn, S. ; Mor, A. ; Barkai, A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c322t-b3eeca4b95693839488c3d592b5e5a4813090cf03bb8f8e7f8d52147e7a8f55c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Brain Stem - physiopathology</topic><topic>Chemical and industrial products toxicology. 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Laryngol. Otol</addtitle><date>1986-09</date><risdate>1986</risdate><volume>100</volume><issue>9</issue><spage>1031</spage><epage>1036</epage><pages>1031-1036</pages><issn>0022-2151</issn><eissn>1748-5460</eissn><coden>JLOTAX</coden><abstract>Auditory Brainstem Evoked Potentials (ABEP) were recorded from 29 adults and children, accidentally exposed to lead through food until approximately a year prior to this study. ABEP were recorded in response to 75 dBHL click presented at rates of 10/sec. and 55/sec. Average values were calculated for peak latency and for interpeak latency differences. Average values of the effect of increasing stimulus rate were calculated as well. Similar values were calculated for normative child and adult control groups. IPLD (I-III) showed the most significant and recurring results, with longer intervals in lead-exposed children compared with their control group. Increasing stimulus rate, on the other hand, affected the adult lead-exposed subjects more than the children. These results may imply an impairment of the auditory system with azonal and myelin involvement. ABEP is suggested as a sensitive detector of subclinical lead exposure effects on the nervous system.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>3760684</pmid><doi>10.1017/S0022215100100519</doi><tpages>6</tpages></addata></record>
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source MEDLINE; Cambridge University Press Journals Complete
subjects Adolescent
Adult
Biological and medical sciences
Brain Stem - physiopathology
Chemical and industrial products toxicology. Toxic occupational diseases
Child
Evoked Potentials, Auditory - drug effects
Female
Humans
Lead Poisoning - diagnosis
Lead Poisoning - physiopathology
Male
Medical sciences
Metals and various inorganic compounds
Middle Aged
Time Factors
Toxicology
title Auditory brainstem evoked potentials in asymptomatic lead-exposed subjects
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