An improved approximation for assessing the statistical significance of molecular sequence features

Using random walk theory, we first establish explicitly the exact distribution of the maximal partial sum of a sequence of independent and identically distributed random variables. This result allows us to obtain a new approximation of the distribution of the local score of one sequence. This approx...

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Veröffentlicht in:Journal of applied probability 2003-06, Vol.40 (2), p.427-441
Hauptverfasser: Mercier, S., Cellier, D., Charlot, D.
Format: Artikel
Sprache:eng
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