Nonenzymatic glucose sensor based on poly(3,4-ethylene dioxythiophene)/electroreduced graphene oxide modified gold electrode

[Display omitted] •A simple, inexpensive and controlable fabrication of PEDOT-ERGO hybrid is reported.•Layered PEDOT-ERGO hybrid was prepared by electrochemical deposition technique on Au.•A non-enzymatic glucose sensor is designed by layered PEDOT-ERGO hybrid structure.•PEDOT-ERGO electrode for glucose sensing shows a low detection limit value of 0.12 μM. In this study, a nonenzymatic glucose sensor based on a Au electrode was modified using layered poly(3,4-ethylene dioxythiophene) (PEDOT) and electroreduced graphene oxide (ERGO). The modified electrode was characterized by X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), and energy-dispersive X-ray spectroscopy (EDS). The electrochemical performance of the electrode material was evaluated to assess its use in glucose sensor applications. In addition, the effect of layer numbers of the layered composite on glucose activity was investigated. The monolayer PEDOT–ERGO nanocomposite exhibited high current density, high sensitivity, and low detection limit of approximately 5 mA cm−2, 696.9 μA mM−1 cm−2, and 0.12 μM, respectively. Moreover, an electrode interference test was conducted in the presence of various interfering species such as ascorbic acid, uric acid, dopamine, and H2O2, revealing excellent selectivity of the nonenzymatic glucose sensor. Thus, the PEDOT–ERGO modified Au electrode could be utilized as a promising nonenzymatic glucose biosensor.