Cutaneous Malignancies in People of Color: A Review of Dermatofibrosarcoma Protuberans and Kaposi Sarcoma

Purpose of Review This literature review aims to address the epidemiological differences, clinical presentations, and treatment outcomes of dermatofibrosarcoma protuberans (DFSP) and Kaposi sarcoma (KS) among people of color (POC), who are underrepresented in skin cancer research. The purpose is to bridge existing knowledge gaps and enhance the understanding of these malignancies in POC. Recent Findings A comprehensive review of literature from 1990 to 2023 revealed significant disparities in the incidence and management of DFSP and KS among POC. Findings indicate a two-fold higher incidence of DFSP in Black patients compared to Whites and a notable predominance of the pigmented Bednar tumor subtype. Similarly, KS shows a six-fold increase in incidence among Black males in the southern U.S. Both cancers tend to present at later stages in POC, with larger tumor sizes at diagnosis. There are also treatment disparities; for instance, Mohs micrographic surgery in DFSP shows a recurrence rate of only 1%, compared to 6.3–8.8% with wide local excision. Furthermore, survival rates for KS are significantly lower among Black patients, with a one-year survival rate of 71.50% compared to 84.26% in Whites. Summary This review highlights significant racial disparities in skin cancer outcomes. Disparities in treatment access and the impact of socioeconomic factors on health outcomes are evident. Enhanced training in dermatology, focusing on POC and increased representation in research are vital. Equitable healthcare can be promoted through awareness, education on sun protection, and addressing systemic healthcare disparities.