A Novel Photothermal Nanocrystals of Cu7S4 Hollow Structure for Efficient Ablation of Cancer Cells

Cu2-x S nanocrystals(NCs), characterized by low cost, low toxicity, high stability and high photothermal conversion efficiency, provide promising platforms as photothermal agents. Herein, a novel twostep synthesis has been developed for Cu7S4 nanocrystals with hollow structure using the as-prepared...

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Veröffentlicht in:Nano-micro letters 2014-04, Vol.6 (2), p.169-179
Hauptverfasser: Song, Guosheng, Han, Linbo, Zou, Weiwei, Xiao, Zhiyin, Huang, XiaoJuan, Qin, Zongyi, Zou, Rujia, Hu, Junqing
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container_end_page 179
container_issue 2
container_start_page 169
container_title Nano-micro letters
container_volume 6
creator Song, Guosheng
Han, Linbo
Zou, Weiwei
Xiao, Zhiyin
Huang, XiaoJuan
Qin, Zongyi
Zou, Rujia
Hu, Junqing
description Cu2-x S nanocrystals(NCs), characterized by low cost, low toxicity, high stability and high photothermal conversion efficiency, provide promising platforms as photothermal agents. Herein, a novel twostep synthesis has been developed for Cu7S4 nanocrystals with hollow structure using the as-prepared copper nanoparticles as starting a solid precursor followed by hot-injection of sulfide source.The Cu7S4 NCs exhibit intense absorption band at Near-infrared(NIR) wavelengths due to localized surface plasmon resonance(LSPR)mode, which can effectively convert 980 nm-laser energy into heat.Moreover, the localized high temperature created by Cu7S4 NCs under NIR irradiation could result in efficient photothermal ablation(PTA) of cancer cells in vivo, demonstrating a novel and promising photothermal nanomaterials.
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subjects Engineering
Nanoscale Science and Technology
Nanotechnology
Nanotechnology and Microengineering
title A Novel Photothermal Nanocrystals of Cu7S4 Hollow Structure for Efficient Ablation of Cancer Cells
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