Mechanistic investigation of oxidation of metronidazole and tinidazole with N-bromosuccinimide in acid medium: A kinetic approach

Metronidazole (MTZ) and tinidazole (TNZ) belong to nitroimidazole group of drugs used to treat infections such as ameobiasis, giardiasis and trichomoniasis. The kinetics of oxidation of MTZ and TNZ with N -bromosuccinimide (NBS) in perchloric acid medium has been investigated at 308 K. A 1:1 stoichi...

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Veröffentlicht in:Journal of the Iranian Chemical Society 2009-06, Vol.6 (2), p.277-287
Hauptverfasser: Mohana, K. N., Ramdas Bhandarkar, P. M.
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Sprache:eng
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