Molecular profiling of non-genotoxic hepatocarcinogenesis using differential display reverse transcription-polymerase chain reaction (ddRT-PCR)

The technique of differential display reverse transcription-polymerase chain reaction (ddRT-PCR) has been used to produce unique profiles of up-regulated and down-regulated gene expression in the liver of male Wistar rats following short term exposure to the non-genotoxic hepatocarcinogens, phenobar...

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Veröffentlicht in:	European journal of drug metabolism and pharmacokinetics 1997-10, Vol.22 (4), p.329-333
Hauptverfasser:	Rockett, J C, Esdaile, D J, Gibson, G G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carcinogens - toxicity DNA, Neoplasm - chemistry DNA, Neoplasm - genetics Liver Neoplasms, Experimental - chemically induced Liver Neoplasms, Experimental - genetics Male Models, Molecular Mutagens - toxicity Phenobarbital - toxicity Polymerase Chain Reaction Pyrimidines - toxicity Rats Rats, Wistar RNA, Messenger - biosynthesis
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