Pulsed estrogen therapy: pharmacokinetics of intranasal 17-beta-estradiol (S21400) in postmenopausal women and comparison with oral and transdermal formulations

Pharmacokinetics of estradiol and estrone were assessed in postmenopausal women receiving S21400, a novel 17beta-estradiol formulation administered by nasal route; the results were compared with those obtained with oral and transdermal routes. Thirty six women received three treatments: a specified...

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Veröffentlicht in:	European journal of drug metabolism and pharmacokinetics 1999-07, Vol.24 (3), p.265-271
Hauptverfasser:	Devissaguet, J P, Brion, N, Lhote, O, Deloffre, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Cutaneous Administration, Intranasal Administration, Oral Aged Cross-Over Studies Estradiol - administration & dosage Estradiol - pharmacokinetics Female Humans Middle Aged Postmenopause
Online-Zugang:	Volltext
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