Differential cytotoxicity of Combretastatins A1 and A4 in two daunorubicin-resistant P388 cell lines

Combretastatin A4, a novel anti-mitotic agent was effective against two P388 cell lines with acquired resistance to daunorubicin. In contrast, Combretastatin A1, a close structural analogue of A4, showed a high degree of cross-resistance. Combretastatin A1 was also more efficient at increasing intra...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer chemotherapy and pharmacology 1990, Vol.26 (1), p.79-81
Hauptverfasser:	MCGOWN, A. T, FOX, B. W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Antineoplastic Agents, Phytogenic - pharmacology Biological and medical sciences Cell Survival - drug effects Daunorubicin - pharmacology Drug Interactions Drug Resistance - genetics General aspects Leukemia P388 - genetics Medical sciences Mice Pharmacology. Drug treatments Stilbenes - pharmacology Tumor Cells, Cultured - drug effects Vinca Alkaloids - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!