Tissue distribution of doxorubicin associated with polyisohexylcyanoacrylate nanoparticles

The body distribution of i.v. doxorubicin depends mainly on the physicochemical characteristics of the molecule. However, entrapment of that cytostatic drug inside polyalkylcyanoacrylate nanoparticles has been shown to modify its distribution profoundly in the mouse. Polysiohexylcyanoacrylate nanopa...

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Veröffentlicht in:	Cancer chemotherapy and pharmacology 1990-01, Vol.26 (1), p.13-18
Hauptverfasser:	VERDUN, C, BRASSEUR, F, VRANCKX, H, COUVREUR, P, ROLAND, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Autoradiography Biological and medical sciences Chromatography, High Pressure Liquid Cyanoacrylates Doxorubicin - administration & dosage Doxorubicin - pharmacokinetics Doxorubicin - urine Drug Carriers Feces - analysis General aspects Injections, Intravenous Medical sciences Mice Particle Size Pharmacology. Drug treatments Tissue Distribution
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