Enhanced Apoptosis in Transformed Human Lung Fibroblasts after Exposure to Sodium Butyrate

Simian virus-transformed human cells, WI-38 VA13A, showed a dose-dependent induction of apoptosis and reduction in cell numbers after exposure to sodium butyrate. Apoptosis was confirmed by ApopTag staining, isolation of apoptotic envelopes, and immunofluorescent staining with an antibody specific f...

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Veröffentlicht in:	In vitro cellular & developmental biology. Animal 1996-09, Vol.32 (8), p.505-513
Hauptverfasser:	Thomas, Graham L., Henley, Anna, Rowland, Tami C., Sahai, Animesh, Griffin, Martin, Birckbichler, Paul J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aneuploidy Apoptosis Biomarkers - analysis Butyrates Butyrates - toxicity Butyric Acid Cell culture techniques Cell cycle Cell Cycle - drug effects Cell Division - drug effects Cell growth Cell Line, Transformed Cell Nucleus - drug effects Cell Nucleus - ultrastructure Cultured cells Diploidy Fibroblasts - drug effects Fluorescent Antibody Technique, Indirect Giant cells Growth, Differentiation and Senescence Humans Lung Sodium Transglutaminases - analysis
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