Holter monitoring in ankylosing spondylitis patients during methylprednisolone pulse therapy
Sudden death following steroid pulse therapy has been recently reported. Continuous electrocardiographic recording was performed 24 hours before, during, and 24 hours after each one to three high dose intravenous methyl prednisolone pulses administered of five patients with severe ankylosing spondyl...
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| Veröffentlicht in: | Clinical rheumatology 1984-03, Vol.3 (1), p.29-31 |
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| container_title | Clinical rheumatology |
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| creator | Nasswetter, G Piñeiro, D J Garcia Morteo, O M Maldonado Cocco, J A Barreira, J C Vazquez Blanco, M |
| description | Sudden death following steroid pulse therapy has been recently reported. Continuous electrocardiographic recording was performed 24 hours before, during, and 24 hours after each one to three high dose intravenous methyl prednisolone pulses administered of five patients with severe ankylosing spondylitis unresponsive to conventional therapy. No increase in supraventricular or ventricular arrhythmias was observed. Bradyarrhythmias, conduction disturbances or ischemic changes were not found. Cardiovascular symptoms did not occur in any case; there were no significative changes in any of the clinical controls. Transient elevations of serum glucose were observed in all patients. Although a transient increase in potassium and decrease in sodium urinary excretion was noted, serum levels remained within normal values. |
| doi_str_mv | 10.1007/BF02715692 |
| format | Article |
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Continuous electrocardiographic recording was performed 24 hours before, during, and 24 hours after each one to three high dose intravenous methyl prednisolone pulses administered of five patients with severe ankylosing spondylitis unresponsive to conventional therapy. No increase in supraventricular or ventricular arrhythmias was observed. Bradyarrhythmias, conduction disturbances or ischemic changes were not found. Cardiovascular symptoms did not occur in any case; there were no significative changes in any of the clinical controls. Transient elevations of serum glucose were observed in all patients. Although a transient increase in potassium and decrease in sodium urinary excretion was noted, serum levels remained within normal values.</description><identifier>ISSN: 0770-3198</identifier><identifier>EISSN: 1434-9949</identifier><identifier>DOI: 10.1007/BF02715692</identifier><identifier>PMID: 6467850</identifier><language>eng</language><publisher>Germany</publisher><subject>Adolescent ; Adult ; Arrhythmias, Cardiac - chemically induced ; Electrocardiography ; Humans ; Male ; Methylprednisolone - adverse effects ; Prospective Studies ; Spondylitis, Ankylosing - drug therapy</subject><ispartof>Clinical rheumatology, 1984-03, Vol.3 (1), p.29-31</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c282t-2b7de2a12e07e281396cd1084612da48ebdb157c4776da84b67c69a2d94c83d3</citedby><cites>FETCH-LOGICAL-c282t-2b7de2a12e07e281396cd1084612da48ebdb157c4776da84b67c69a2d94c83d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6467850$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nasswetter, G</creatorcontrib><creatorcontrib>Piñeiro, D J</creatorcontrib><creatorcontrib>Garcia Morteo, O M</creatorcontrib><creatorcontrib>Maldonado Cocco, J A</creatorcontrib><creatorcontrib>Barreira, J C</creatorcontrib><creatorcontrib>Vazquez Blanco, M</creatorcontrib><title>Holter monitoring in ankylosing spondylitis patients during methylprednisolone pulse therapy</title><title>Clinical rheumatology</title><addtitle>Clin Rheumatol</addtitle><description>Sudden death following steroid pulse therapy has been recently reported. Continuous electrocardiographic recording was performed 24 hours before, during, and 24 hours after each one to three high dose intravenous methyl prednisolone pulses administered of five patients with severe ankylosing spondylitis unresponsive to conventional therapy. No increase in supraventricular or ventricular arrhythmias was observed. Bradyarrhythmias, conduction disturbances or ischemic changes were not found. Cardiovascular symptoms did not occur in any case; there were no significative changes in any of the clinical controls. Transient elevations of serum glucose were observed in all patients. Although a transient increase in potassium and decrease in sodium urinary excretion was noted, serum levels remained within normal values.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Arrhythmias, Cardiac - chemically induced</subject><subject>Electrocardiography</subject><subject>Humans</subject><subject>Male</subject><subject>Methylprednisolone - adverse effects</subject><subject>Prospective Studies</subject><subject>Spondylitis, Ankylosing - drug therapy</subject><issn>0770-3198</issn><issn>1434-9949</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkM9LwzAARoMos04v3oWchWqSpvlx1OGcMPCyo1DSJnPRNglJeuh_7-aGnj4ePL7DA-AWoweMEH98XiLCcc0kOQMFphUtpaTyHBSIc1RWWIpLcJXSF0KICIlnYMYo46JGBfhY-T6bCAfvbPbRuk9oHVTue-p9OlAK3umpt9kmGFS2xuUE9fhrDibvpj5Eo51NvvfOwDD2ycC8M1GF6RpcbNWeb047B5vly2axKtfvr2-Lp3XZEUFySVquDVGYGMQNEbiSrNMYCcow0YoK0-oW17yjnDOtBG0Z75hUREvaiUpXc3B_vO2iTymabROiHVScGoyaQ6DmP9BevjvKYWwHo__UU5HqB-6HYr8</recordid><startdate>198403</startdate><enddate>198403</enddate><creator>Nasswetter, G</creator><creator>Piñeiro, D J</creator><creator>Garcia Morteo, O M</creator><creator>Maldonado Cocco, J A</creator><creator>Barreira, J C</creator><creator>Vazquez Blanco, M</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>198403</creationdate><title>Holter monitoring in ankylosing spondylitis patients during methylprednisolone pulse therapy</title><author>Nasswetter, G ; Piñeiro, D J ; Garcia Morteo, O M ; Maldonado Cocco, J A ; Barreira, J C ; Vazquez Blanco, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c282t-2b7de2a12e07e281396cd1084612da48ebdb157c4776da84b67c69a2d94c83d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Arrhythmias, Cardiac - chemically induced</topic><topic>Electrocardiography</topic><topic>Humans</topic><topic>Male</topic><topic>Methylprednisolone - adverse effects</topic><topic>Prospective Studies</topic><topic>Spondylitis, Ankylosing - drug therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nasswetter, G</creatorcontrib><creatorcontrib>Piñeiro, D J</creatorcontrib><creatorcontrib>Garcia Morteo, O M</creatorcontrib><creatorcontrib>Maldonado Cocco, J A</creatorcontrib><creatorcontrib>Barreira, J C</creatorcontrib><creatorcontrib>Vazquez Blanco, M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Clinical rheumatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nasswetter, G</au><au>Piñeiro, D J</au><au>Garcia Morteo, O M</au><au>Maldonado Cocco, J A</au><au>Barreira, J C</au><au>Vazquez Blanco, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Holter monitoring in ankylosing spondylitis patients during methylprednisolone pulse therapy</atitle><jtitle>Clinical rheumatology</jtitle><addtitle>Clin Rheumatol</addtitle><date>1984-03</date><risdate>1984</risdate><volume>3</volume><issue>1</issue><spage>29</spage><epage>31</epage><pages>29-31</pages><issn>0770-3198</issn><eissn>1434-9949</eissn><abstract>Sudden death following steroid pulse therapy has been recently reported. Continuous electrocardiographic recording was performed 24 hours before, during, and 24 hours after each one to three high dose intravenous methyl prednisolone pulses administered of five patients with severe ankylosing spondylitis unresponsive to conventional therapy. No increase in supraventricular or ventricular arrhythmias was observed. Bradyarrhythmias, conduction disturbances or ischemic changes were not found. Cardiovascular symptoms did not occur in any case; there were no significative changes in any of the clinical controls. Transient elevations of serum glucose were observed in all patients. Although a transient increase in potassium and decrease in sodium urinary excretion was noted, serum levels remained within normal values.</abstract><cop>Germany</cop><pmid>6467850</pmid><doi>10.1007/BF02715692</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0770-3198 |
| ispartof | Clinical rheumatology, 1984-03, Vol.3 (1), p.29-31 |
| issn | 0770-3198 1434-9949 |
| language | eng |
| recordid | cdi_crossref_primary_10_1007_BF02715692 |
| source | MEDLINE; SpringerLink Journals |
| subjects | Adolescent Adult Arrhythmias, Cardiac - chemically induced Electrocardiography Humans Male Methylprednisolone - adverse effects Prospective Studies Spondylitis, Ankylosing - drug therapy |
| title | Holter monitoring in ankylosing spondylitis patients during methylprednisolone pulse therapy |
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