Influence of the pharmacokinetic model on the quantification of the Gd-DTPA uptake rate in brain tumours using direct T1 measurements

After a bolus injection of Gd-DTPA, a fast tracer uptake in rat brain tumours was already observed during the tracer bolus passage. For the quantification of the uptake rate constant, pharmacokinetic models are commonly used. For a good quantification, the changes of the plasma tracer concentration...

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Veröffentlicht in:	Magma (New York, N.Y.) N.Y.), 1998-08, Vol.6 (1), p.37-43
Hauptverfasser:	Rozijn, T H, van der Sanden, B P, Heerschap, A, Creyghton, J H, Bovée, W M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain Neoplasms - metabolism Contrast Media - pharmacokinetics Gadolinium DTPA - blood Gadolinium DTPA - pharmacokinetics Magnetic Resonance Imaging - methods Mathematical Computing Models, Biological Rats
Online-Zugang:	Volltext
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