Comparison of serum dependency of transformed insect cell lines of different degrees of malignancy
The rate of growth of four malignantly transformed insect cell lines was correlated with their dependence on serum in the medium. Highly malignant lines, in terms of LT50for insects injected with the cells, were less affected in vitro by low levels of serum than were the lines that killed more slowl...
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| Veröffentlicht in: | In Vitro 1983-10, Vol.19 (10), p.775-781 |
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| container_title | In Vitro |
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| creator | Tsang, K.R Brooks, M.A |
| description | The rate of growth of four malignantly transformed insect cell lines was correlated with their dependence on serum in the medium. Highly malignant lines, in terms of LT50for insects injected with the cells, were less affected in vitro by low levels of serum than were the lines that killed more slowly in vivo. The two most malignant lines could be adapted to growth in medium without serum, whereas the others could not. |
| doi_str_mv | 10.1007/BF02618097 |
| format | Article |
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Highly malignant lines, in terms of LT50for insects injected with the cells, were less affected in vitro by low levels of serum than were the lines that killed more slowly in vivo. The two most malignant lines could be adapted to growth in medium without serum, whereas the others could not.</description><identifier>ISSN: 0073-5655</identifier><identifier>EISSN: 2327-4328</identifier><identifier>EISSN: 1475-2689</identifier><identifier>DOI: 10.1007/BF02618097</identifier><language>eng</language><publisher>Rockville, MD: Tissue Culture Association, Inc</publisher><subject>Animal cells ; animal physiology ; arthropods ; Biochemistry. Physiology. Immunology ; Biological and medical sciences ; Biotechnology ; Cell cultures. Hybridization. Fusion ; Cell growth ; Cell lines ; Cultured cells ; Embryos ; entomology ; Establishment of new cell lines, improvement of cultural methods, mass cultures ; Eukaryotic cell cultures ; Fundamental and applied biological sciences. Psychology ; Insect behavior ; Insecta ; Insects ; Invertebrates ; Methods. Procedures. Technologies ; Molecular and cellular biology ; Physiology. Development ; Subcultures ; Time dependence ; Transformed cell line</subject><ispartof>In Vitro, 1983-10, Vol.19 (10), p.775-781</ispartof><rights>Copyright 1983 Tissue Culture Association</rights><rights>1984 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c262t-d11865641e9715f019646742b645d34abfa95816a88ba25c3840ca9fa08d73b13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/4292742$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/4292742$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,776,780,799,27903,27904,57995,58228</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=9413966$$DView record in Pascal Francis$$Hfree_for_read</backlink></links><search><creatorcontrib>Tsang, K.R</creatorcontrib><creatorcontrib>Brooks, M.A</creatorcontrib><title>Comparison of serum dependency of transformed insect cell lines of different degrees of malignancy</title><title>In Vitro</title><description>The rate of growth of four malignantly transformed insect cell lines was correlated with their dependence on serum in the medium. Highly malignant lines, in terms of LT50for insects injected with the cells, were less affected in vitro by low levels of serum than were the lines that killed more slowly in vivo. The two most malignant lines could be adapted to growth in medium without serum, whereas the others could not.</description><subject>Animal cells</subject><subject>animal physiology</subject><subject>arthropods</subject><subject>Biochemistry. Physiology. Immunology</subject><subject>Biological and medical sciences</subject><subject>Biotechnology</subject><subject>Cell cultures. Hybridization. Fusion</subject><subject>Cell growth</subject><subject>Cell lines</subject><subject>Cultured cells</subject><subject>Embryos</subject><subject>entomology</subject><subject>Establishment of new cell lines, improvement of cultural methods, mass cultures</subject><subject>Eukaryotic cell cultures</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Insect behavior</subject><subject>Insecta</subject><subject>Insects</subject><subject>Invertebrates</subject><subject>Methods. Procedures. Technologies</subject><subject>Molecular and cellular biology</subject><subject>Physiology. Development</subject><subject>Subcultures</subject><subject>Time dependence</subject><subject>Transformed cell line</subject><issn>0073-5655</issn><issn>2327-4328</issn><issn>1475-2689</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1983</creationdate><recordtype>article</recordtype><recordid>eNpFkEtLw0AUhQdRsFY3rgWzcCVE5_1YavEFBRfadbiZzJSUZBJm4qL_3imRurpwzndfB6Frgh8Ixurx-RVTSTQ26gQtKKOq5IzqU7TIJiuFFOIcXaS0w5hhSckC1auhHyG2aQjF4Ivk4k9fNG50oXHB7g_aFCEkP8TeNUUbkrNTYV3XFV0bXDoATeu9iy5MuXEb3Sz20LXbAHnGJTrz0CV39VeXaPP68r16L9efbx-rp3VpqaRT2RCipZCcOKOI8JgYyaXitJZcNIxD7cEITSRoXQMVlmmOLRgPWDeK1YQt0f0818Yhpeh8Nca2h7ivCK4O6VT_6WT4boZHSBY6n3-0bTp2GE6YkTJjNzO2S9MQjzanhubTsn072x6GCrY5xmrzRTFheQ-VSij2C5yJdns</recordid><startdate>198310</startdate><enddate>198310</enddate><creator>Tsang, K.R</creator><creator>Brooks, M.A</creator><general>Tissue Culture Association, Inc</general><general>Tissue Culture Association</general><scope>FBQ</scope><scope>IQODW</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>198310</creationdate><title>Comparison of serum dependency of transformed insect cell lines of different degrees of malignancy</title><author>Tsang, K.R ; Brooks, M.A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c262t-d11865641e9715f019646742b645d34abfa95816a88ba25c3840ca9fa08d73b13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1983</creationdate><topic>Animal cells</topic><topic>animal physiology</topic><topic>arthropods</topic><topic>Biochemistry. Physiology. Immunology</topic><topic>Biological and medical sciences</topic><topic>Biotechnology</topic><topic>Cell cultures. Hybridization. Fusion</topic><topic>Cell growth</topic><topic>Cell lines</topic><topic>Cultured cells</topic><topic>Embryos</topic><topic>entomology</topic><topic>Establishment of new cell lines, improvement of cultural methods, mass cultures</topic><topic>Eukaryotic cell cultures</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Insect behavior</topic><topic>Insecta</topic><topic>Insects</topic><topic>Invertebrates</topic><topic>Methods. Procedures. Technologies</topic><topic>Molecular and cellular biology</topic><topic>Physiology. Development</topic><topic>Subcultures</topic><topic>Time dependence</topic><topic>Transformed cell line</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tsang, K.R</creatorcontrib><creatorcontrib>Brooks, M.A</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>CrossRef</collection><jtitle>In Vitro</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tsang, K.R</au><au>Brooks, M.A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of serum dependency of transformed insect cell lines of different degrees of malignancy</atitle><jtitle>In Vitro</jtitle><date>1983-10</date><risdate>1983</risdate><volume>19</volume><issue>10</issue><spage>775</spage><epage>781</epage><pages>775-781</pages><issn>0073-5655</issn><eissn>2327-4328</eissn><eissn>1475-2689</eissn><abstract>The rate of growth of four malignantly transformed insect cell lines was correlated with their dependence on serum in the medium. Highly malignant lines, in terms of LT50for insects injected with the cells, were less affected in vitro by low levels of serum than were the lines that killed more slowly in vivo. The two most malignant lines could be adapted to growth in medium without serum, whereas the others could not.</abstract><cop>Rockville, MD</cop><pub>Tissue Culture Association, Inc</pub><doi>10.1007/BF02618097</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0073-5655 |
| ispartof | In Vitro, 1983-10, Vol.19 (10), p.775-781 |
| issn | 0073-5655 2327-4328 1475-2689 |
| language | eng |
| recordid | cdi_crossref_primary_10_1007_BF02618097 |
| source | Jstor Complete Legacy; Springer Nature - Complete Springer Journals |
| subjects | Animal cells animal physiology arthropods Biochemistry. Physiology. Immunology Biological and medical sciences Biotechnology Cell cultures. Hybridization. Fusion Cell growth Cell lines Cultured cells Embryos entomology Establishment of new cell lines, improvement of cultural methods, mass cultures Eukaryotic cell cultures Fundamental and applied biological sciences. Psychology Insect behavior Insecta Insects Invertebrates Methods. Procedures. Technologies Molecular and cellular biology Physiology. Development Subcultures Time dependence Transformed cell line |
| title | Comparison of serum dependency of transformed insect cell lines of different degrees of malignancy |
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