Antitumor effects of inhibitors of arachidonic acid cascade on experimentally induced intestinal tumors

The antitumor action of inhibitors of cyclooxygenase (indomethacin) and lipoxygenase activity (nordihydroguaiaretic acid) of arachidonic acid cascade was investigated in the chemically induced large bowel tumors in Sprague-Dawley rats. Indomethacin treatment completely prevented the carcinogenic eff...

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Veröffentlicht in:	Diseases of the colon & rectum 1987, Vol.30 (1), p.43-46
Hauptverfasser:	BIRKENFELD, S, ZALTSMAN, Y. A, KRISPIN, M, ZAKUT, H, ZOR, U, KOHEN, F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Arachidonic Acids - antagonists & inhibitors Biological and medical sciences Catechols - therapeutic use Chemotherapy Indomethacin - therapeutic use Intestinal Neoplasms - chemically induced Intestinal Neoplasms - drug therapy Male Masoprocol - therapeutic use Medical sciences Methylazoxymethanol Acetate - analogs & derivatives Pharmacology. Drug treatments Prostaglandin Antagonists Rats Rats, Inbred Strains
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