Cefazolin-induced pseudomembranous colitis resulting in perforation of the sigmoid colon

The seventh case of probable cefazolin-induced pseudomembranous colitis is reported. Perforation of the colon necessitated sigmoid resection. The postoperative course was protracted, and illustrates the difficulty of managing advanced pseudomembranous colitis when the oral route of antibiotic admini...

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Veröffentlicht in:Diseases of the colon & rectum 1986-02, Vol.29 (2), p.140-143
Hauptverfasser: OSLER, T, LOTT, D, BORDLEY, J, LYNCH, F, ELLSWORTH, C, KOZAK, A
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container_end_page 143
container_issue 2
container_start_page 140
container_title Diseases of the colon & rectum
container_volume 29
creator OSLER, T
LOTT, D
BORDLEY, J
LYNCH, F
ELLSWORTH, C
KOZAK, A
description The seventh case of probable cefazolin-induced pseudomembranous colitis is reported. Perforation of the colon necessitated sigmoid resection. The postoperative course was protracted, and illustrates the difficulty of managing advanced pseudomembranous colitis when the oral route of antibiotic administration is not available. Although rare, pseudomembranous colitis related to cefazolin administration is a potentially fatal complication. The routine use of prophylactic antibiotics must be weighed against this possibility.
doi_str_mv 10.1007/BF02555402
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Perforation of the colon necessitated sigmoid resection. The postoperative course was protracted, and illustrates the difficulty of managing advanced pseudomembranous colitis when the oral route of antibiotic administration is not available. Although rare, pseudomembranous colitis related to cefazolin administration is a potentially fatal complication. 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Perforation of the colon necessitated sigmoid resection. The postoperative course was protracted, and illustrates the difficulty of managing advanced pseudomembranous colitis when the oral route of antibiotic administration is not available. Although rare, pseudomembranous colitis related to cefazolin administration is a potentially fatal complication. The routine use of prophylactic antibiotics must be weighed against this possibility.</abstract><cop>Secaucus, NJ</cop><pub>Springer</pub><pmid>3510836</pmid><doi>10.1007/BF02555402</doi><tpages>4</tpages></addata></record>
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source MEDLINE; Alma/SFX Local Collection; Journals@Ovid Complete
subjects Aged
Biological and medical sciences
Cefazolin - adverse effects
Cefazolin - therapeutic use
Colectomy
Drug toxicity and drugs side effects treatment
Enterocolitis, Pseudomembranous - chemically induced
Enterocolitis, Pseudomembranous - complications
Enterocolitis, Pseudomembranous - diagnostic imaging
Enterocolitis, Pseudomembranous - surgery
Female
Humans
Intestinal Perforation - diagnostic imaging
Intestinal Perforation - etiology
Intestinal Perforation - surgery
Medical sciences
Pharmacology. Drug treatments
Premedication
Sigmoid Diseases - diagnostic imaging
Sigmoid Diseases - etiology
Sigmoid Diseases - surgery
Tomography, X-Ray Computed
Toxicity: digestive system
title Cefazolin-induced pseudomembranous colitis resulting in perforation of the sigmoid colon
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