Cefazolin-induced pseudomembranous colitis resulting in perforation of the sigmoid colon
The seventh case of probable cefazolin-induced pseudomembranous colitis is reported. Perforation of the colon necessitated sigmoid resection. The postoperative course was protracted, and illustrates the difficulty of managing advanced pseudomembranous colitis when the oral route of antibiotic admini...
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Veröffentlicht in: | Diseases of the colon & rectum 1986-02, Vol.29 (2), p.140-143 |
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container_title | Diseases of the colon & rectum |
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creator | OSLER, T LOTT, D BORDLEY, J LYNCH, F ELLSWORTH, C KOZAK, A |
description | The seventh case of probable cefazolin-induced pseudomembranous colitis is reported. Perforation of the colon necessitated sigmoid resection. The postoperative course was protracted, and illustrates the difficulty of managing advanced pseudomembranous colitis when the oral route of antibiotic administration is not available. Although rare, pseudomembranous colitis related to cefazolin administration is a potentially fatal complication. The routine use of prophylactic antibiotics must be weighed against this possibility. |
doi_str_mv | 10.1007/BF02555402 |
format | Article |
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Perforation of the colon necessitated sigmoid resection. The postoperative course was protracted, and illustrates the difficulty of managing advanced pseudomembranous colitis when the oral route of antibiotic administration is not available. Although rare, pseudomembranous colitis related to cefazolin administration is a potentially fatal complication. The routine use of prophylactic antibiotics must be weighed against this possibility.</description><identifier>ISSN: 0012-3706</identifier><identifier>EISSN: 1530-0358</identifier><identifier>DOI: 10.1007/BF02555402</identifier><identifier>PMID: 3510836</identifier><identifier>CODEN: DICRAG</identifier><language>eng</language><publisher>Secaucus, NJ: Springer</publisher><subject>Aged ; Biological and medical sciences ; Cefazolin - adverse effects ; Cefazolin - therapeutic use ; Colectomy ; Drug toxicity and drugs side effects treatment ; Enterocolitis, Pseudomembranous - chemically induced ; Enterocolitis, Pseudomembranous - complications ; Enterocolitis, Pseudomembranous - diagnostic imaging ; Enterocolitis, Pseudomembranous - surgery ; Female ; Humans ; Intestinal Perforation - diagnostic imaging ; Intestinal Perforation - etiology ; Intestinal Perforation - surgery ; Medical sciences ; Pharmacology. 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Perforation of the colon necessitated sigmoid resection. The postoperative course was protracted, and illustrates the difficulty of managing advanced pseudomembranous colitis when the oral route of antibiotic administration is not available. Although rare, pseudomembranous colitis related to cefazolin administration is a potentially fatal complication. The routine use of prophylactic antibiotics must be weighed against this possibility.</description><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Cefazolin - adverse effects</subject><subject>Cefazolin - therapeutic use</subject><subject>Colectomy</subject><subject>Drug toxicity and drugs side effects treatment</subject><subject>Enterocolitis, Pseudomembranous - chemically induced</subject><subject>Enterocolitis, Pseudomembranous - complications</subject><subject>Enterocolitis, Pseudomembranous - diagnostic imaging</subject><subject>Enterocolitis, Pseudomembranous - surgery</subject><subject>Female</subject><subject>Humans</subject><subject>Intestinal Perforation - diagnostic imaging</subject><subject>Intestinal Perforation - etiology</subject><subject>Intestinal Perforation - surgery</subject><subject>Medical sciences</subject><subject>Pharmacology. Drug treatments</subject><subject>Premedication</subject><subject>Sigmoid Diseases - diagnostic imaging</subject><subject>Sigmoid Diseases - etiology</subject><subject>Sigmoid Diseases - surgery</subject><subject>Tomography, X-Ray Computed</subject><subject>Toxicity: digestive system</subject><issn>0012-3706</issn><issn>1530-0358</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkMFLwzAUh4Moc04v3oUePAnVl6RJs6MOp8LAi4K3kiYvM9I2JWkP-tdb2Zinx-P7-B0-Qi4p3FKA8u5hDUwIUQA7InMqOOTAhTomcwDKcl6CPCVnKX1NLzAoZ2TGBQXF5Zx8rNDpn9D4LvedHQ3arE842tBiW0fdhTFlZsKDT1nENDaD77aZ77IeowtRDz50WXDZ8IlZ8ts2ePvnh-6cnDjdJLzY3wV5Xz--rZ7zzevTy-p-kxtO6ZAjlcZIaoRaKsmdQ6FLyVUtLEiUjhWMFSiZYEutDF8WyiJa6xSrS-GYAL4gN7tdE0NKEV3VR9_q-F1RqP7qVP91JvlqJ_dj3aI9qPscE7_ec52MbtwUwPh00FTJVMFK_gskQGzV</recordid><startdate>19860201</startdate><enddate>19860201</enddate><creator>OSLER, T</creator><creator>LOTT, D</creator><creator>BORDLEY, J</creator><creator>LYNCH, F</creator><creator>ELLSWORTH, C</creator><creator>KOZAK, A</creator><general>Springer</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19860201</creationdate><title>Cefazolin-induced pseudomembranous colitis resulting in perforation of the sigmoid colon</title><author>OSLER, T ; LOTT, D ; BORDLEY, J ; LYNCH, F ; ELLSWORTH, C ; KOZAK, A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c311t-e16cc61c589863ffe5a7638b5d06e6f24224e62529a8c3948deeddf82b75f2503</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Cefazolin - adverse effects</topic><topic>Cefazolin - therapeutic use</topic><topic>Colectomy</topic><topic>Drug toxicity and drugs side effects treatment</topic><topic>Enterocolitis, Pseudomembranous - chemically induced</topic><topic>Enterocolitis, Pseudomembranous - complications</topic><topic>Enterocolitis, Pseudomembranous - diagnostic imaging</topic><topic>Enterocolitis, Pseudomembranous - surgery</topic><topic>Female</topic><topic>Humans</topic><topic>Intestinal Perforation - diagnostic imaging</topic><topic>Intestinal Perforation - etiology</topic><topic>Intestinal Perforation - surgery</topic><topic>Medical sciences</topic><topic>Pharmacology. Drug treatments</topic><topic>Premedication</topic><topic>Sigmoid Diseases - diagnostic imaging</topic><topic>Sigmoid Diseases - etiology</topic><topic>Sigmoid Diseases - surgery</topic><topic>Tomography, X-Ray Computed</topic><topic>Toxicity: digestive system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>OSLER, T</creatorcontrib><creatorcontrib>LOTT, D</creatorcontrib><creatorcontrib>BORDLEY, J</creatorcontrib><creatorcontrib>LYNCH, F</creatorcontrib><creatorcontrib>ELLSWORTH, C</creatorcontrib><creatorcontrib>KOZAK, A</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Diseases of the colon & rectum</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>OSLER, T</au><au>LOTT, D</au><au>BORDLEY, J</au><au>LYNCH, F</au><au>ELLSWORTH, C</au><au>KOZAK, A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cefazolin-induced pseudomembranous colitis resulting in perforation of the sigmoid colon</atitle><jtitle>Diseases of the colon & rectum</jtitle><addtitle>Dis Colon Rectum</addtitle><date>1986-02-01</date><risdate>1986</risdate><volume>29</volume><issue>2</issue><spage>140</spage><epage>143</epage><pages>140-143</pages><issn>0012-3706</issn><eissn>1530-0358</eissn><coden>DICRAG</coden><abstract>The seventh case of probable cefazolin-induced pseudomembranous colitis is reported. Perforation of the colon necessitated sigmoid resection. The postoperative course was protracted, and illustrates the difficulty of managing advanced pseudomembranous colitis when the oral route of antibiotic administration is not available. Although rare, pseudomembranous colitis related to cefazolin administration is a potentially fatal complication. The routine use of prophylactic antibiotics must be weighed against this possibility.</abstract><cop>Secaucus, NJ</cop><pub>Springer</pub><pmid>3510836</pmid><doi>10.1007/BF02555402</doi><tpages>4</tpages></addata></record> |
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source | MEDLINE; Alma/SFX Local Collection; Journals@Ovid Complete |
subjects | Aged Biological and medical sciences Cefazolin - adverse effects Cefazolin - therapeutic use Colectomy Drug toxicity and drugs side effects treatment Enterocolitis, Pseudomembranous - chemically induced Enterocolitis, Pseudomembranous - complications Enterocolitis, Pseudomembranous - diagnostic imaging Enterocolitis, Pseudomembranous - surgery Female Humans Intestinal Perforation - diagnostic imaging Intestinal Perforation - etiology Intestinal Perforation - surgery Medical sciences Pharmacology. Drug treatments Premedication Sigmoid Diseases - diagnostic imaging Sigmoid Diseases - etiology Sigmoid Diseases - surgery Tomography, X-Ray Computed Toxicity: digestive system |
title | Cefazolin-induced pseudomembranous colitis resulting in perforation of the sigmoid colon |
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