Cell membrane localization of sterols with conventional and unusual side chains in two marine demonsponges

Subcellular fractionation by differential centrifugation was performed on two previously unstudied marine sponges that predominantly contain either conventional (Reniera sp.) or unconventional (Pseudaxinyssa sp.) sterols. Direct evidence for the presence of unconventional sterols with C24 alkylated...

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Veröffentlicht in:Lipids 1988-08, Vol.23 (8), p.750-754
Hauptverfasser: Lawson, Mishelle P., Stoilov, Ivan L., Thompson, Janice E., Djerassi, Carl
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container_issue 8
container_start_page 750
container_title Lipids
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creator Lawson, Mishelle P.
Stoilov, Ivan L.
Thompson, Janice E.
Djerassi, Carl
description Subcellular fractionation by differential centrifugation was performed on two previously unstudied marine sponges that predominantly contain either conventional (Reniera sp.) or unconventional (Pseudaxinyssa sp.) sterols. Direct evidence for the presence of unconventional sterols with C24 alkylated side chains in the cellular membranes ofPseudaxinyssa sp. is provided, but the presence of unconventional sterols in sponge membranes is shown not to be a universal feature of the Porifera. Possible structural and functional roles of unconventional lipid molecules in sponge cell membranes are discussed.
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title Cell membrane localization of sterols with conventional and unusual side chains in two marine demonsponges
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