Effect of biotin on ammonia intoxication in rats and mice

The effects of biotin on ammonia concentration in blood and brain were evaluated in hyperammonemic rats and mice. Rats were injected with 5 mmol/kg BW of ammonium acetate, and mice were injected with 10 mmol/kg BW. Increases in blood ammonia levels in rats 15-30 min after ammonia loading were preven...

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Veröffentlicht in:	Journal of gastroenterology 1995-06, Vol.30 (3), p.351-355
Hauptverfasser:	Nagamine, T, Saito, S, Kaneko, M, Sekiguchi, T, Sugimoto, H, Takehara, K, Takagi, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetates - metabolism Acetates - toxicity Amino Acids - drug effects Amino Acids - metabolism Ammonia - metabolism Analysis of Variance Animals Aspartic Acid - metabolism Biotin - pharmacology Brain - drug effects Brain - metabolism Dipeptides - pharmacology Glutamic Acid - metabolism Glutamine - metabolism Male Mice Mice, Inbred Strains Rats Rats, Sprague-Dawley
Online-Zugang:	Volltext
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