Administration of anti-inflammatory compounds in silastic capsules

Eleven compounds, within hollow capsules of polydimethylsiloxane (Silastic), have been studied with regard to their rate of release and anti-inflammatory activity in the Adjuvant Arthritic (AA) rat. All of the compounds diffused through the capsule wall to some extent with cortisone acetate exhibiti...

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Veröffentlicht in:	Agents and Actions 1977-12, Vol.7 (5-6), p.555-562
Hauptverfasser:	Jones, R C, Datko, L J
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Anti-Inflammatory Agents - administration & dosage Arthritis, Experimental - drug therapy Capsules Indomethacin - administration & dosage Injections, Subcutaneous Male Naproxen - administration & dosage Phenylbutazone - administration & dosage Rats Silicone Elastomers
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