Dihydroergotamine and heparin or heparin alone for the prevention of postoperative thromboembolism in gynecology
The efficacy of combined dihydroergotamine and heparin (DHE-heparin) medication (2500 IU sodium heparin and 0.5 mg DHE, both given subcutaneously twice daily) or low doses of heparin (5,000 IU of sodium heparin given subcutaneously thrice daily) in preventing postoperative thromboembolic complicatio...
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| Veröffentlicht in: | Archives of Gynecology 1980-01, Vol.230 (1), p.15-19 |
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| container_title | Archives of Gynecology |
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| creator | Hohl, M K Lüscher, K P Annaheim, M Fridrich, R Gruber, U F |
| description | The efficacy of combined dihydroergotamine and heparin (DHE-heparin) medication (2500 IU sodium heparin and 0.5 mg DHE, both given subcutaneously twice daily) or low doses of heparin (5,000 IU of sodium heparin given subcutaneously thrice daily) in preventing postoperative thromboembolic complications was investigated in a prospective, randomized trial in 125 patients over the age of 40 years undergoing elective major gynecological surgery. The I125-fibrinogen uptake test was used for the diagnosis of deep vein thrombosis. There was no statistically significant difference in the incidence of thromboembolism between the groups. Major bleeding occurred less often (p < 0.05) in the DHE-heparin group. |
| doi_str_mv | 10.1007/BF02108594 |
| format | Article |
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The I125-fibrinogen uptake test was used for the diagnosis of deep vein thrombosis. There was no statistically significant difference in the incidence of thromboembolism between the groups. 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The I125-fibrinogen uptake test was used for the diagnosis of deep vein thrombosis. There was no statistically significant difference in the incidence of thromboembolism between the groups. Major bleeding occurred less often (p < 0.05) in the DHE-heparin group.</description><subject>Adult</subject><subject>Aged</subject><subject>Dihydroergotamine - administration & dosage</subject><subject>Dihydroergotamine - therapeutic use</subject><subject>Drug Therapy, Combination</subject><subject>Female</subject><subject>Heparin - administration & dosage</subject><subject>Heparin - therapeutic use</subject><subject>Humans</subject><subject>Middle Aged</subject><subject>Postoperative Complications</subject><subject>Thromboembolism - prevention & control</subject><issn>0170-9925</issn><issn>1432-0711</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1980</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkEFLAzEQhYMotdRevAt7FlYnyabbHLW2KhS86HnJZidtZHcTkrWw_95ISx0YZpj3vTk8Qm4pPFCA8vF5A4zCUsjigkxpwVkOJaWXZAq0hFxKJq7JPMZvSMUlhyVMyKQs-EIIOiX-xe7HJjgMOzeozvaYqb7J9uhVsH3mwnlVrUuiSZdhj5kPeMB-sC4xJvMuDs5jUIM9YNKD62qHqVsbuyyZd2OP2rVuN96QK6PaiPPTnJGvzfpz9ZZvP17fV0_bXLMlG3JtUBtWm0WNpRGNUrQ0RmhVoGBYaFYwkEIpIUoExjVqzWotjFG00SCl5jNyf_yrg4sxoKl8sJ0KY0Wh-guu-g8uwXdH2P_UHTZn9BQT_wWwDmxw</recordid><startdate>19800101</startdate><enddate>19800101</enddate><creator>Hohl, M K</creator><creator>Lüscher, K P</creator><creator>Annaheim, M</creator><creator>Fridrich, R</creator><creator>Gruber, U F</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19800101</creationdate><title>Dihydroergotamine and heparin or heparin alone for the prevention of postoperative thromboembolism in gynecology</title><author>Hohl, M K ; Lüscher, K P ; Annaheim, M ; Fridrich, R ; Gruber, U F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c282t-cfecf2bf6be7f5daa17ff5ca4e52e4c242095aa557e023cecc2bc5ffa1dc099c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1980</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Dihydroergotamine - administration & dosage</topic><topic>Dihydroergotamine - therapeutic use</topic><topic>Drug Therapy, Combination</topic><topic>Female</topic><topic>Heparin - administration & dosage</topic><topic>Heparin - therapeutic use</topic><topic>Humans</topic><topic>Middle Aged</topic><topic>Postoperative Complications</topic><topic>Thromboembolism - prevention & control</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hohl, M K</creatorcontrib><creatorcontrib>Lüscher, K P</creatorcontrib><creatorcontrib>Annaheim, M</creatorcontrib><creatorcontrib>Fridrich, R</creatorcontrib><creatorcontrib>Gruber, U F</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Archives of Gynecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hohl, M K</au><au>Lüscher, K P</au><au>Annaheim, M</au><au>Fridrich, R</au><au>Gruber, U F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dihydroergotamine and heparin or heparin alone for the prevention of postoperative thromboembolism in gynecology</atitle><jtitle>Archives of Gynecology</jtitle><addtitle>Arch Gynecol</addtitle><date>1980-01-01</date><risdate>1980</risdate><volume>230</volume><issue>1</issue><spage>15</spage><epage>19</epage><pages>15-19</pages><issn>0170-9925</issn><eissn>1432-0711</eissn><abstract>The efficacy of combined dihydroergotamine and heparin (DHE-heparin) medication (2500 IU sodium heparin and 0.5 mg DHE, both given subcutaneously twice daily) or low doses of heparin (5,000 IU of sodium heparin given subcutaneously thrice daily) in preventing postoperative thromboembolic complications was investigated in a prospective, randomized trial in 125 patients over the age of 40 years undergoing elective major gynecological surgery. The I125-fibrinogen uptake test was used for the diagnosis of deep vein thrombosis. There was no statistically significant difference in the incidence of thromboembolism between the groups. Major bleeding occurred less often (p < 0.05) in the DHE-heparin group.</abstract><cop>Germany</cop><pmid>7436551</pmid><doi>10.1007/BF02108594</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0170-9925 |
| ispartof | Archives of Gynecology, 1980-01, Vol.230 (1), p.15-19 |
| issn | 0170-9925 1432-0711 |
| language | eng |
| recordid | cdi_crossref_primary_10_1007_BF02108594 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Adult Aged Dihydroergotamine - administration & dosage Dihydroergotamine - therapeutic use Drug Therapy, Combination Female Heparin - administration & dosage Heparin - therapeutic use Humans Middle Aged Postoperative Complications Thromboembolism - prevention & control |
| title | Dihydroergotamine and heparin or heparin alone for the prevention of postoperative thromboembolism in gynecology |
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