Direct evidence of oxidative damage in acute and chronic phases of experimental colitis in rats

During inflammatory colitis in man and experimental animals, the production of free radicals increases. This study evaluated the histological pattern and biochemical parameters of oxidative damage during acute and chronic colitis induced by 2,4,-trinitrobenzenesulfonic acid + ethanol in rats. On the...

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Veröffentlicht in:	Digestive diseases and sciences 1996-06, Vol.41 (6), p.1204-1211
Hauptverfasser:	Loguercio, C, D'Argenio, G, Delle Cave, M, Cosenza, V, Della Valle, N, Mazzacca, G, del Vecchio Blanco, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Animals Chronic Disease Colitis - chemically induced Colitis - metabolism Colitis - pathology Colon - metabolism Colon - pathology Ethanol Glutathione - metabolism Intestinal Mucosa - metabolism Intestinal Mucosa - pathology Lipid Peroxidation Male Malondialdehyde - metabolism Oxidative Stress Rats Rats, Wistar Superoxide Dismutase - metabolism Trinitrobenzenesulfonic Acid
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