p53 mutations in flat- and polypoid-type colorectal tumors detected by temperature-gradient gel electrophoresis

Reports of cases of flat-type colorectal tumors are increasing in Japan, but almost nothing has been elucidated about the genetic abnormalities of these tumors. In this study, we have examined p53 mutations in six cases of colon cancer cell lines, 22 cases of flat-type colorectal tumors, and 27 case...

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