Different concentrations of local anaesthetics have different modes of action on human lymphocytes

Lidocaine and Bupivacaine inhibit in vitro 3H-TdR incorporation into peripheral lymphocytes, in a dose dependent ratio, either under PHA stimulus or not. Lidocaine added to cultures at various times from PHA stimulus show a reduced inhibition only when added after the 24th hour. This suggests a sens...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Agents and Actions 1983-06, Vol.13 (4), p.333-341
Hauptverfasser:	Ramus, G V, Cesano, L, Barbalonga, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anesthetics, Local - pharmacology Bupivacaine - pharmacology Calcium - physiology Cells, Cultured Female Humans In Vitro Techniques Lidocaine - pharmacology Lymphocytes - drug effects Male Middle Aged Mitosis - drug effects Phytohemagglutinins - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!